Background: |
This gene encodes a protein that belongs to a conserved family of potassium channel tetramerization domain (KCTD)-containing proteins. The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a keratin-binding protein, for degradation via polyubiquitinylation. A mutation in this gene is associated with autosomal dominant myoclonic dystonia 26. |
Applications: |
ELISA, IHC |
Name of antibody: |
KCTD17 |
Immunogen: |
Fusion protein of human KCTD17 |
Full name: |
potassium channel tetramerization domain containing 17 |
SwissProt: |
Q8N5Z5 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human gastric cancer; |
IHC Recommend dilution: |
10-50 |