Fusion protein corresponding to a region derived from 294-493 amino acids of human DUS2 |
技術(shù)規(guī)格
Full name: |
dihydrouridine synthase 2 |
Synonyms: |
SMM1; DUS2L; URLC8 |
Swissprot: |
Q9NX74 |
Gene Accession: |
BC006527 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. |