Background: |
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
KCNJ2 |
Immunogen: |
Synthetic peptide of human KCNJ2 |
Full name: |
potassium voltage-gated channel subfamily J member 2 |
Synonyms: |
IRK1; LQT7; SQT3; ATFB9; HHIRK1; KIR2.1; HHBIRK1 |
SwissProt: |
P63252 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
48 kDa |
WB Positive control: |
A549 cell lysate |
WB Recommended dilution: |
500-2000 |