技術規(guī)格
Background:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms.
Applications:
ELISA, WB, IHC
Name of antibody:
KCNH6
Immunogen:
Fusion protein of human KCNH6
Full name:
potassium voltage-gated channel, subfamily H (eag-related), member 6
Synonyms:
ERG2; ERG-2; HERG2; Kv11.2; hERG-2
SwissProt:
Q9H252
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human breast cancer
IHC Recommend dilution:
35-150
WB Predicted band size:
110 kDa
WB Positive control:
Hepg2 and HT-29 cells
WB Recommended dilution:
200-1000