Background: |
Voltage-gated potassium channels play a variety of important roles in human health and disease. KCNE1, also known as MinK, belongs to a family of small transmembrane proteins (KCNE1, 2, 3, 4, and KCNE1L) that modulate the activity of several voltage-gated K+ channels. KCNE1 functions as the modulatory β-subunit of the pore-forming α-subunit KCNQ1, and alters several biophysical properties of KCNQ1 channels. Research studies have shown that several inherited mutations in KCNE1 result in long QT syndrome and deafness. |
Applications: |
WB |
Name of antibody: |
KCNE1 |
Immunogen: |
Fusion protein of human KCNE1 |
Full name: |
potassium voltage-gated channel, Isk-related family, member 1 |
Synonyms: |
KCNE1; FLJ18426; FLJ38123; FLJ94103; ISK; JLNS; JLNS2; LQT2/5; LQT5; MGC33114; MinK |
SwissProt: |
P15382 |
WB Predicted band size: |
15 kDa |
WB Positive control: |
Mouse heart and testis tissue |
WB Recommended dilution: |
500-2000 |