技術規格
Background: |
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
JUP |
Immunogen: |
Fusion protein of human JUP |
Full name: |
junction plakoglobin |
Synonyms: |
DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12 |
SwissProt: |
P14923 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human cervical cancer and Human lung cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
82 kDa |
WB Positive control: |
Mouse heart tissue and Hela cells, HUVEC cells and mouse skin tissue |
WB Recommended dilution: |
1000-5000 |