中文名稱:CHRM1抗原(重組蛋白)
英文名稱:CHRM1 Antigen (Recombinant Protein)
儲 存:冷凍(-20℃)
相關類別:抗原
概述
Fusion protein corresponding to a region derived from 220-366 amino acids of human CHRM1 |
技術規格
Full name: |
cholinergic receptor, muscarinic 1 |
Synonyms: |
M1; HM1; M1R |
Swissprot: |
P11229 |
Gene Accession: |
BC007740 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13 |