中文名稱:CEACAM8抗原(重組蛋白)
英文名稱:CEACAM8 Antigen (Recombinant Protein)
儲(chǔ) 存:冷凍(-20℃)
相關(guān)類別:抗原
概述
Fusion protein corresponding to a region derived from 35-320 amino acids of human CEACAM8 |
技術(shù)規(guī)格
Full name:
carcinoembryonic antigen related cell adhesion molecule 8
Synonyms:
CD67; CGM6; CD66b; NCA-95
Swissprot:
P31997
Gene Accession:
BC026263
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
CEA-related cell adhesion molecule 8 (CEACAM8) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a molecular mass of of 95kD and is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. Therefore CEACAM8 could serve as a marker for granulocyte activities. Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B domains.