中文名稱: 兔抗ABCG5多克隆抗體
英文名稱: Anti-ABCG5 rabbit polyclonal antibody
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: ABCG5
反應(yīng)種屬: Human
克隆類型: rabbit polyclonal
Background: |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. |
Applications: |
ELISA, IHC |
Name of antibody: |
ABCG5 |
Immunogen: |
Synthetic peptide of human ABCG5 |
Full name: |
ATP-binding cassette, sub-family G (WHITE), member 5 |
Synonyms: |
STSL |
SwissProt: |
Q9H222 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |