反應(yīng)種屬: Human
技術(shù)規(guī)格
Background: |
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM]. |
Applications: |
WB, IHC, IF, FC |
Name of antibody: |
PDE1B |
Immunogen: |
Fusion protein of human PDE1B |
Full name: |
phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1 |
Synonyms: |
PDE1B1; PDES1B; HEL-S-79p |
SwissProt: |
Q01064 |
IHC positive control: |
human kidney tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
61 kDa |
WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |